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Melissa McCarthy

Tammy

Susan Sarandon

Pearl

Kathy Bates

Lenore

Mark Duplass

Bobby

Gary Cole

Earl

Allison Janney

Deb

Dan Aykroyd

Don

Sandra Oh

Susanne

Nat Faxon

Greg

Toni Collette

Missi

Ben Falcone

Keith Morgan

Sarah Baker

Becky

Rich Williams

Larry

Steve Little

Jet Ski Rental Guy

Dakota Lee

Kathleen

Mark L. Young

Jesse

Mia Rose Frampton

Karen

Steve Mallory

Cashier

Big Al Hall

Possum Creek Bluegrass Band

Jones Smith

Possum Creek Bluegrass Band

Joe Baxter

Possum Creek Bluegrass Band

Benjamin Chontos

Possum Creek Bluegrass Band

Sean Gould

Possum Creek Bluegrass Band

Keith Welborn

DJ

Oscar Gale

Javier

Justin Smith

Paramedic

Willie Hill

Prison Guard

Zach Hanner

Man at Blue Post Bar-B-Que

Jason Vail

Man at Blue Post Bar-B-Que

Leon Lamar

Old Man with Walker

Larry Dorf

Officer Mannis

Ricky Muse

Officer Curtis

Barbara Weetman

Officer Carty

William Flaman

La Grange Bail Cop

Rey Hernandez

Cop at Lakehouse

Penn Holderness

News Anchor

Michelle Li

News Reporter

Raven Angeline Whisnant

Charlotte

Damon Jones

Jerry Miller

Sandy McCarthy

Old Lady Leaving a Bar

Margo Passas

Old Lady Leaving a Bar

Sheila Brothers

Connie (uncredited)

Rob Springer

Gene the Cook (uncredited)

Cricket Ellis

Lunchroom Lady (uncredited)

Kaitlyn Christian

Canoe Teen (uncredited)

J.R. Rodriguez

Kentucky Trooper (uncredited)

Michelle Rivera Huckaby

Arresting Cop (uncredited)

David Andrew Nash

Morningside Guard (uncredited)